Individual mammalian cells contain billions of protein molecules, which must be synthesized, deployed, and removed with ...

Inside each cell of the human body are proteins that control which genes are expressed at the right place and time. However, intriguingly, many of the most important proteins involved in gene ...

While its origins are often associated with the post-war reconstruction of Europe, the style was also adopted globally as a powerful expression of modernity and national identity in many newly ...

Immunogenicity refers to a biopharmaceutical’s ability to generate an immune response upon administration. It is a major concern in biologics development because it can cause adverse events in ...

Scientists have for the first time looked deep into the protein structure that may determine our vision - and discovered that it is much more dynamic than previously thought. RBP3 not only changes its ...

The intrinsically disordered proteins (IDPs) do not attain a stable secondary or tertiary structure and rapidly change their conformation, making structure prediction particularly challenging. These ...

In 2020, news headlines repeated John Moult’s words at the end of a stunning competition: Artificial intelligence had “solved” a long-standing grand challenge in biology, protein structure prediction.

Announcing a new publication for Acta Materia Medica journal. Proteins are essential macromolecules that perform functions according to their conformational dynamics. Studying the conformational ...

Generating all-atom protein structures is a significant challenge in de novo protein design. Current generative models have improved significantly for backbone generation but remain difficult to solve ...