With recent advances in sequencing, genotyping arrays, and imputation, GWAS now aim to identify associations with rare and uncommon genetic variants. Here, we describe and evaluate a class of ...

The books Lies, Damn Lies, and Statistics (Wheeler, 1976) and Damned Lies and Statistics (Best, 2001) have raised questions about whether statistics can be trusted. A number of educated people today, ...

Significance testing, with appropriate multiple testing correction, is currently the most convenient method for summarizing the evidence for association between a disease and a genetic variant.

The books Lies, Damn Lies, and Statistics (Wheeler, 1976) and Damned Lies and Statistics (Best, 2001) have raised questions about whether statistics can be trusted. A number of educated people today, ...

The Mann-Whitney U Test, also known as the Wilcoxon Rank Sum Test, is a non-parametric statistical test used to compare two samples or groups. The Mann-Whitney U Test assesses whether two sampled ...

Post-hoc testing is carried out after a statistical analysis where you have performed multiple significance tests, ‘post-hoc’ coming from the Latin “after this”. Post-hoc analysis represents a way to ...

This is a preview. Log in through your library . Abstract A nonparametric statistical test of the performance of ordinations is adapted and extended from the work of Feigin and Cohen (1978). Two ...

Statistical significance is a critical concept in data analysis and research. In essence, it’s a measure that allows researchers to assess whether the results of an experiment or study are due to ...

Misuse of statistics in medical and sports science research is common and may lead to detrimental consequences to healthcare. Many authors, editors and peer reviewers of medical papers will not have ...

Adam Hayes, Ph.D., CFA, is a financial writer with 15+ years Wall Street experience as a derivatives trader. Besides his extensive derivative trading expertise, Adam is an expert in economics and ...