New structural insights reveal how human respiratory chain complexes assemble

A new study shows how one of the cell's most important energy-producing machines is built. Researchers at Karolinska ...

My Students Write Their Papers Backwards

My job is to help them move beyond their assumptions, in literature and everything else.

Polygon Labs' $250M Coinme Acquisition Shows Stablecoin Payments Entering A New Phase In 2026

Blockchain firm Polygon Labs (CRYPTO: POL) said on Tuesday it would buy crypto payments company Coinme and crypto ...

GBP/JPY Price Forecast: RSI eases from overbought territory as upside momentum cools

The British Pound (GBP) weakens against the Japanese Yen (JPY) on Thursday as renewed intervention speculation supports the ...
IEEE

HighMPNN: A Graph Neural Network Approach for Structure-Constrained Cyclic Peptide Sequence Design

Abstract: Cyclic peptides become attractive therapeutic candidates due to their diverse biological activities. However, existing deep learning-based sequence design models, such as ProteinMPNN, are ...
IEEE

Protein-Binding RNA Prediction Based on Integrated Sequence-Structure-Function Pre-Training

Abstract: RNA binding proteins (RBPs) play a crucial role in regulating biological functions through their interactions with specific RNAs, significantly impacting various life processes.
eLife

Conformational Variability of HIV-1 Env Trimer and Viral Vulnerability

In silico antibody accessibility analysis indicates that ectodomain epitopes are transiently exposed, while MPER epitopes are virtually always occluded in the pre-fusion trimer.