A new strategy to beat lung cancer: Chemists develop first-in-class inhibitor targeting a key epigenetic regulator

A research team has made a breakthrough in epigenetic drug discovery. The researchers have successfully developed a ...

Small molecules could treat Crohn's disease by mimicking a protective gene variant

An estimated 3 million Americans have an inflammatory bowel disease (IBD) such as Crohn's disease or ulcerative colitis. But ...
eLife

GMCL1 controls 53BP1 stability and modulates taxane sensitivity

GMCL1-dependent degradation of 53BP1 suppresses mitotic surveillance, tuning p53 activation thresholds that govern cell fate decisions and cellular responses after mitosis.
CIO

How adaptive infrastructure is evolving capabilities at the speed of business

Old-school infrastructure can’t keep up with AI, so smart teams are breaking it into modular pieces that AI agents can ...

The Truth Behind the Will of D: How Elbaf, Nika, Joy Boy, and the Giant Straw Hat are Connected in One Piece?

The latest revelations about the Will of D suggest that the Elbaf nation is connected to the D clan. Discover more about the ...