The formation of pores by a particular protein, gasdermin D, plays a key role in inflammatory reactions. During its activation, an inhibitory part is split off. More than 30 of the remaining protein ...

Researchers have identified a previously unknown inflammatory mechanism that may drive the aggressiveness and relapse of small cell lung cancer. Small cell lung cancer (SCLC) is among the most ...

A research team led by Professor Jong Kyoung Kim and Yujin Jeong (PhD candidate), from the Department of Life Sciences at Pohang University of Science and Technology (POSTECH) in collaboration with ...

Small cell lung cancer (SCLC) is one of the most aggressive forms of lung cancer, with a five-year survival rate of only 5%. Despite this poor prognosis, SCLC is initially highly responsive to ...

Researchers at the NYU Pain Research Center have identified a mechanism that underlies inflammation and pain in the colon, and demonstrated that blocking a key receptor from entering colon cells can ...

About 50% of the adult population throughout the world over the age of 70 years has chronic kidney disease (CKD) and renal fibrosis. Both CKD and renal fibrosis begin as pyroptosis, during which a ...

In a recent review published in the European Journal of Endocrinology, researchers discussed current research on the relationship between human obesity and inflammation of the hypothalamus. In 2022, ...

If you've ever fought off an infection or iced a sprained knee, you know something about inflammation. But you might not know its importance to heart and brain health. Inflammation has been linked to ...

While the anti-inflammatory effects of cannabinoids have been shown in previous studies, exactly how they exerted those effects remained unclear. Now, researchers from the Friedrich Schiller ...