Physiological and optogenetic dissection of discrete locus coeruleus neuronal populations reveals a functional disassociation, with heterogeneous engagement of locus coeruleus neurons in either fear ...
Small and seemingly specialized, the brain's locus coeruleus (LC) region has been stereotyped for its outsized export of the arousal-stimulating neuromodulator norepinephrine. In a new paper and with ...
A tiny region in the brain works like a reset button that separates memory of one meaningful event from the next. Without this reset mechanism, moments could blur together and lead to the kinds of ...
Life may unfold as a continuous stream, but our memories tell a different story. We do not recall the past as one long, unbroken text. Instead, we remember it as a series of meaningful events, like ...
Deep within the brainstem is a structure no bigger than a grain of rice, the locus coeruleus. The LC is often referred to as the “blue spot” because of a distinct blue pigment produced from its inner ...
Perceiving events in the "right" way is directly linked to better memory, suggesting that improving locus coeruleus function is an effective target for either protecting or recovering memory function.
Older adults appear more easily distracted by irrelevant information than younger people when they experience stress or powerful emotions-- and a specific network in the brain recently identified as ...
The locus coeruleus is emerging as a major new area of research interest, with many important functions such as regulating our attention and sleep. Anyone with insomnia knows the impatience and ...
A critical but vulnerable region in the brain appears to be the first place affected by late onset Alzheimer's disease and may be more important for maintaining cognitive function in later life than ...