High levels of calcium are toxic to cells and contribute to loss of neurons in Alzheimer’s disease. A new JCI Insight study ...

Nerve cells regulate and routinely refresh the collection of calcium channels that enable them to send messages across circuit connections. The nervous system works because neurons communicate across ...

Neuronal calcium sensors (NCS) comprise a pivotal family of EF‐hand calcium‐binding proteins that translate transient fluctuations in intracellular Ca²⁺ into specific cellular responses. These ...

When a neuron fires, calcium flows into the cell in a wave that sweeps along the cell body. Images of this infragranular neuron were obtained three times per second by two-dimensional scanning with a ...

Immune cell responses to bacteria affect the intrinsic excitability of rat neuronal subtypes differently. Calcium-activated SK channels in pyramidal cells were modulated by microglia and upregulated, ...

When triggered by an odor, rapid changes in membrane voltage and intracellular calcium ion levels occur in nematode olfactory neurons, causing membrane voltage sensors and calcium ion sensors to ...

Researchers have discovered how an ion channel in the brain's neurons has a kind of 'molecular memory', which contributes to the formation and preservation of lifelong memories. The researchers have ...

Our biceps and our brain cells may have more in common than previously thought. New research led by the Lippincott-Schwartz Lab shows that a network of subcellular structures similar to those ...