In this report, we compared the contribution of the MAPK and PI3K pathways in ligand-dependent and oncogenic c-Kit signalling. We focussed on cell proliferation and tumour cell survival, ...
Adenoid cystic carcinoma (ACC) is characterized by persistent, relentless growth and a high rate of eventual metastasis. In contrast, polymorphous low-grade adenocarcinoma (PLGA) has a much lower risk ...
c-Kit (CD117), a type III receptor tyrosine kinase (RTK), is involved in intracellular signaling. c-Kit and its ligand stem cell factor (SCF) are essential for embryonic development and the ...
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